| International Standard Book Number |
9780525536093 electronic book
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| International Standard Book Number |
9780525536079 hardcover
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| International Standard Book Number |
0525536078 hardcover
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| Dewey Decimal Classification Number |
362.1968/311 23/eng/20241115
|
| Personal Name |
Smith, Jennie Erin, author.
|
| Title Statement |
Valley of forgetting : Alzheimer's families and the search for a cure / Jennie Erin Smith.
|
| Varying Form of Title |
Alzheimer's families and the search for a cure
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| Production, Publication, Distribution, Manufacture, and Copyright Notice |
Ã2025
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| Production, Publication, Distribution, Manufacture, and Copyright Notice |
New York : Riverhead Books, 2025.
|
| Physical Description |
376 pages ; 24 cm
|
| Content Type |
text txt rdacontent
|
| Media Type |
unmediated n rdamedia
|
| Carrier Type |
volume nc rdacarrier
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| Bibliography, Etc. Note |
Includes bibliographical references and index.
|
| Formatted Contents Note |
Curious doctors -- Las familias -- Resilience.
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| Summary, Etc. |
"The riveting account of a community from the remote mountains of Colombia whose rare and fatal genetic mutation is unlocking the secrets of Alzheimer's disease In the 1980s, a neurologist named Francisco Lopera traveled on horseback into the mountains seeking families with symptoms of dementia. For centuries, residents of certain villages near Medellâin had suffered memory loss as they reached middle age, going on to die in their fifties. Lopera discovered that a unique genetic mutation was causing their rare hereditary form of early onset Alzheimer's disease. Over the next forty years of working with the "paisa mutation" kindred, he went on to build a world-class research program in a region beset by violence and poverty. In Valley of Forgetting, Jennie Erin Smith brings readers into the clinic, the laboratories, and the Medellâin trial center where Lopera's patients receive an experimental drug to see if Alzheimer's can be averted. She chronicles the lives of people who care for sick parents, spouses, and siblings, all while struggling to keep their own dreams afloat. These Colombian families have donated hundreds of their loved ones' brains to science and subjected themselves to invasive testing to help uncover how Alzheimer's develops and whether it can be stopped. Findings from this unprecedented effort could hold the key to understanding and treating the disease, though it is unclear what, if anything, the families will receive in return. Smith's immersive storytelling brings this complex drama to life, inviting readers on a scientific journey that is as deeply moving as it is engrossing"-- Provided by publisher.
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| Subject-Personal Name |
Restrepo Lopera, Francisco, 1951-2024.
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| Subject Added Entry - Topical Term |
Biology. sears
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| Subject Added Entry - Topical Term |
Alzheimer's disease.
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| Subject Added Entry - Topical Term |
HEALTH & FITNESS / Diseases & Conditions / Alzheimer's & Dementia. bisacsh
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| Subject Added Entry - Topical Term |
Medicine Research.
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| Subject Added Entry - Topical Term |
Medicine, Experimental.
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| Subject Added Entry - Topical Term |
Alzheimer Disease
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| Subject Added Entry - Topical Term |
Family Support history
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| Subject Added Entry - Topical Term |
Biomedical Research history
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| Subject Added Entry - Topical Term |
Research Subjects psychology
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| Subject Added Entry - Geographical Term |
Colombia
|
| Subject Added Entry - Geographical Term |
Colombia.
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| Index Term-Genre/Form |
Informational works. lcgft
|
| Index Term-Genre/Form |
Personal narratives. lcgft
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| Additional Physical Form Entry |
Online version: Smith, Jennie Erin, 1973- New York : Riverhead Books, [2025] Valley of forgetting (DLC) 2024044616 9780525536093
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| Location |
362.196 SMI 31662001845544
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